How Does Palonosetron Compare to Other Antiemetic Agents?
Palonosetron is often compared to other antiemetic agents such as ondansetron and granisetron. Studies have shown that palonosetron is more effective than these first-generation 5-HT3 antagonists in preventing delayed nausea and vomiting. Its longer duration of action and higher binding affinity to the 5-HT3 receptor make it a preferred choice for many oncologists.