RNAi works through a series of steps: 1. Introduction of siRNA or miRNA: These small RNA molecules are introduced into the cell. 2. Incorporation into the RNA-Induced Silencing Complex (RISC): The RNA molecules are incorporated into a protein complex known as RISC. 3. Target Recognition: The RNA-RISC complex binds to complementary mRNA sequences. 4. mRNA Degradation: The bound mRNA is cleaved and degraded, leading to gene silencing.