The MethylationEPIC BeadChip uses a microarray-based technology to detect methylation status at specific CpG sites. The process involves bisulfite conversion of DNA, which differentiates between methylated and unmethylated cytosines. The converted DNA is then hybridized to the BeadChip, and fluorescent signals are used to determine the methylation status. The data generated can be analyzed to identify differentially methylated regions associated with cancer.
