How Does the Tumor Microenvironment Affect Cancer Progression?
The tumor microenvironment consists of a variety of cells and extracellular components surrounding the tumor. This environment plays a significant role in cancer progression and metastasis. The interactions between cancer cells and other cells, such as immune cells, fibroblasts, and blood vessels, can either suppress or promote tumor growth. For example, cancer-associated fibroblasts can remodel the extracellular matrix, facilitating cancer cell invasion and metastasis.
