The primary mechanism through which Valproic Acid operates is by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. However, in the context of cancer, its significance lies in its ability to inhibit histone deacetylases (HDACs). HDACs play a crucial role in the regulation of gene expression, and their inhibition can lead to cell cycle arrest, differentiation, and apoptosis of cancer cells.
