How has the understanding of the tumor microenvironment influenced cancer therapy?
The tumor microenvironment plays a crucial role in cancer progression and treatment resistance. Recent research has focused on targeting the components of the microenvironment, such as cancer-associated fibroblasts and immune cells, to improve treatment outcomes. Therapies aimed at modifying the microenvironment, such as angiogenesis inhibitors, which block blood vessel formation, have shown promise in inhibiting tumor growth.