Diagnosis of ALCL typically involves a combination of biopsy and imaging studies. A biopsy of the affected tissue is crucial for identifying the characteristic large anaplastic cells. Immunohistochemistry and genetic testing are also used to detect specific markers like CD30 and ALK protein, which help differentiate ALCL from other types of lymphomas. Imaging studies, such as CT or PET scans, are used to assess the extent of the disease.
