Diagnosing Cushing's Disease involves several steps:
1. Clinical Evaluation: A thorough medical history and physical examination. 2. Laboratory Tests: Blood tests to measure cortisol and ACTH levels, a 24-hour urinary free cortisol test, and a low-dose dexamethasone suppression test. 3. Imaging Studies: MRI or CT scans to identify the pituitary tumor or other possible tumors causing ectopic ACTH production.