Several methodologies and frameworks are used for data standardization in cancer research:
Common Data Elements (CDEs): These are standardized terms and definitions that facilitate data sharing and aggregation. The National Cancer Institute (NCI) provides a repository of CDEs for cancer research. Data Models: Frameworks like the OMOP Common Data Model (CDM) help in transforming disparate data into a standardized format. Controlled Vocabularies: Standardized vocabularies and ontologies, such as SNOMED CT and LOINC, ensure consistent data annotation and interpretation. Data Harmonization Tools: Tools like TranSMART and cBioPortal assist in the integration and harmonization of diverse datasets.
