EMT is tightly regulated by a complex interplay of signaling pathways, including Wnt/β-catenin, Notch, and Hedgehog. These pathways interact with the cellular microenvironment and transcription factors to maintain a balance between epithelial and mesenchymal states. Additionally, feedback loops involving microRNAs and other non-coding RNAs play a pivotal role in fine-tuning EMT regulation.