Diagnosing invasive aspergillosis can be challenging due to non-specific symptoms such as fever, cough, and chest pain. Advanced diagnostic tools include imaging techniques like CT scans, which may reveal characteristic signs of lung involvement. Laboratory tests, such as galactomannan and beta-D-glucan assays, are also employed to detect fungal antigens in blood or other body fluids. A definitive diagnosis often requires a tissue biopsy to identify the presence of Aspergillus hyphae.