Interestingly, ketoconazole has found utility in the treatment of certain types of cancer, particularly prostate cancer. This off-label use is due to its ability to inhibit the enzyme cytochrome P450 17A1 (CYP17A1), which plays a crucial role in the biosynthesis of androgens. By reducing androgen levels, ketoconazole can help in slowing the progression of androgen-dependent prostate cancer.
