The diagnosis of LC involves a combination of clinical evaluation, imaging studies, and cerebrospinal fluid analysis: - Clinical Evaluation: Neurological examination to assess neurological deficits. - Imaging Studies: MRI is the preferred imaging modality for detecting LC, often revealing abnormal enhancement of the leptomeninges. - CSF Analysis: Lumbar puncture to collect CSF, which is then analyzed for malignant cells, elevated protein levels, and decreased glucose levels.
