The role of LPL in cancer is complex and multifaceted. Dysregulation of lipid metabolism is a hallmark of cancer, and LPL is a key enzyme in this process. Cancer cells have a high demand for lipids to support rapid cell division and growth. By hydrolyzing triglycerides, LPL provides a source of free fatty acids that can be used for membrane biosynthesis, energy production, and signaling, thus facilitating tumor progression.
