Diagnosis usually involves a combination of methods:
Blood tests to evaluate the overall health and detect abnormalities. Biopsy of the affected lymph node or tissue to confirm the presence of cancerous cells. Imaging studies like CT scans, PET scans, or MRIs to assess the spread of the disease. Bone marrow aspiration to check if cancer has spread to the bone marrow. Flow cytometry to analyze the types of cells in the sample. Cytogenetic analysis to identify genetic abnormalities typical of MCL, such as the translocation t(11;14).
