The method of administration depends on the type of radioisotope and the cancer being treated:
Oral: For example, iodine-131 is often given as a capsule to treat thyroid cancer. Intravenous: Radionuclides like radium-223 are administered via IV injection for bone metastases. Intra-tumoral: In some cases, the radioisotope may be directly placed into or near the tumor.