The Khorana Score is based on five risk factors, each assigned a specific point value:
Site of cancer: Very high-risk sites (stomach, pancreas) are assigned 2 points, high-risk sites (lung, lymphoma, gynecologic, bladder, testicular) are assigned 1 point, and others are assigned 0 points. Platelet count: ≥ 350,000/μL receives 1 point. Hemoglobin levels: White blood cell count: > 11,000/μL receives 1 point. Body mass index (BMI): ≥ 35 kg/m² receives 1 point.
The total score is calculated by summing the points for each risk factor, with higher scores indicating a greater risk of VTE.