UHPLC plays a critical role in the identification and quantification of cancer biomarkers. Biomarkers are biological molecules found in blood, other body fluids, or tissues that signal an abnormal process, condition, or disease. By using UHPLC, researchers can separate and analyze proteins, peptides, and small molecules with high precision. This leads to the discovery of potential biomarkers that could be used for early detection, prognosis, and monitoring of cancer progression.