While the direct role of CACNA1S in cancer is still under investigation, alterations in calcium signaling pathways are known to contribute to cancerous transformations. Abnormal calcium signaling can lead to uncontrolled cell proliferation and resistance to apoptosis, both hallmarks of cancer. Dysregulation of calcium channels, possibly through mutations or altered expression of the CACNA1S gene, may thus play a role in oncogenesis. However, more research is needed to establish a clear link between CACNA1S and specific cancer types.
