Selecting the appropriate somatic CNV caller depends on various factors:
Type of Sequencing Data: Some tools are optimized for whole-genome sequencing, while others work better with targeted or exome sequencing. Computational Resources: The computational requirements of different tools can vary significantly. Specificity and Sensitivity: The balance between false positives and false negatives should be considered based on the study's objectives. User Community and Support: Tools with active user communities and support resources can be easier to troubleshoot and use effectively.
