Is There a Role for Demethylating Agents in Cancer Treatment?
Demethylating agents, such as azacitidine and decitabine, have shown promise in treating certain cancers by reversing abnormal methylation patterns. These drugs can reactivate silenced tumor suppressor genes, thereby inhibiting cancer growth. They are currently used in treating hematological malignancies like myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).
