What Alternatives Exist to Anticholinergic Agents for Symptom Management in Cancer?
There are several alternatives to anticholinergic agents for symptom management in cancer patients. For nausea and vomiting, other classes of medications such as 5-HT3 antagonists (e.g., ondansetron) and NK1 receptor antagonists (e.g., aprepitant) may be used. For managing secretions, options like glycopyrrolate, which has fewer central nervous system effects, may be considered. Non-pharmacological interventions, such as psychosocial support and physical therapy, can also play a critical role in symptom management.