What are Cyclin-Dependent Kinases (CDKs) and their Role in Cancer?
CDKs are a family of protein kinases that, when activated by cyclins, regulate various stages of the cell cycle. In cancer, CDKs can become hyperactive due to mutations or overexpression of cyclins, leading to uncontrolled cell proliferation. Drugs known as CDK inhibitors have been developed to target these enzymes, offering a promising approach to cancer treatment by halting the progression of the cell cycle in cancer cells.
