What Are Prodrugs and Their Role in Cancer Therapy?
Prodrugs are designed to enhance the bioavailability of drugs, particularly those with poor solubility or stability, and to reduce systemic toxicity by targeting the release of the active drug to specific tissues. In cancer therapy, prodrugs can be engineered to exploit the unique microenvironment of tumors, such as the acidic pH, the presence of specific enzymes, or the overexpression of certain proteins.
