What are Some Examples of Bispecific Antibodies in Clinical Use?
Several BsAbs have shown promising results in clinical trials and have been approved for use:
Blinatumomab: Approved for treating certain types of acute lymphoblastic leukemia (ALL), it targets CD19 on B cells and CD3 on T cells. Amivantamab: Approved for non-small cell lung cancer (NSCLC), it targets epidermal growth factor receptor (EGFR) and mesenchymal-epithelial transition factor (MET).
