What Are Some Examples of Errors Leading to Specific Cancers?
Several types of cancer are associated with specific errors in DNA replication. For example:
Mutations in the BRCA1 and BRCA2 genes are linked to increased risk of breast and ovarian cancers. Mutations in the TP53 gene, which codes for the p53 protein, are found in over 50% of human cancers and are associated with various cancer types. Mutations in the APC gene are commonly found in colorectal cancers.
