Several small molecule drugs have been approved for cancer treatment. Examples include:
- Imatinib: Used to treat chronic myeloid leukemia (CML) by inhibiting the BCR-ABL fusion protein. - Erlotinib: Targets the epidermal growth factor receptor (EGFR) and is used in non-small cell lung cancer. - Sunitinib: Inhibits multiple receptor tyrosine kinases and is used in renal cell carcinoma and gastrointestinal stromal tumors.