Over the years, the IBCSG has made several notable contributions to breast cancer research. Some key achievements include: - Pioneering studies on adjuvant therapy, which have improved outcomes for patients with early-stage breast cancer. - Research on the role of endocrine therapy in hormone receptor-positive breast cancer. - Investigating the efficacy of various chemotherapy regimens and targeted therapies. - Studies on the long-term effects of breast cancer treatments, including the impact on quality of life and survivorship.