What are Some Key Genomic Databases Used in Cancer Research?
The Cancer Genome Atlas (TCGA): This comprehensive database provides genomic, epigenomic, transcriptomic, and proteomic data from various types of cancers. TCGA has been instrumental in identifying genetic mutations and molecular subtypes of cancers. COSMIC (Catalogue Of Somatic Mutations In Cancer): COSMIC contains information on somatic mutations in human cancer. It helps researchers understand the mutation spectrum and frequency in different cancers. ICGC (International Cancer Genome Consortium): ICGC aims to coordinate large-scale cancer genome studies across the globe. It provides data on genetic, epigenetic, and transcriptomic alterations in various cancers. GDC (Genomic Data Commons): The GDC provides a unified data repository that enables data sharing across cancer genomic studies. It integrates data from TCGA, TARGET, and other cancer research projects. cBioPortal: This resource offers visualization and analysis tools for large-scale cancer genomics data. It provides users with access to multidimensional cancer genomics datasets, aiding in data interpretation and hypothesis generation.
