What Are Some Notable Success Stories in Cancer Genomics?
There have been several success stories in cancer genomics that highlight its potential:
Chronic Myeloid Leukemia (CML): The discovery of the BCR-ABL fusion gene led to the development of imatinib (Gleevec), a targeted therapy that has dramatically improved outcomes for CML patients. Melanoma: Identifying mutations in the BRAF gene paved the way for targeted therapies like vemurafenib, significantly improving survival rates for patients with BRAF-mutant melanoma. Lung Cancer: Genomic profiling has identified several actionable mutations (e.g., EGFR, ALK) that can be targeted with specific inhibitors, offering new treatment options for patients.
