What are the Advantages of Single Cell Bisulfite Sequencing in Cancer Research?
scBS-seq offers several advantages for cancer research: - Heterogeneity Analysis: It allows researchers to study the heterogeneity of DNA methylation within a tumor, providing insights into the diversity of cancer cell populations. - Epigenetic Landscape: It provides a comprehensive view of the epigenetic landscape of individual cancer cells, which can help in identifying novel biomarkers and therapeutic targets. - Clonal Evolution: It aids in understanding the clonal evolution of cancer by tracking epigenetic changes over time and in response to treatment. - Microenvironment Interactions: It enables the study of interactions between cancer cells and their microenvironment at the epigenetic level.
