What are the Applications of HLA Typing in Cancer Therapy?
HLA typing has several applications in cancer therapy:
Transplant Compatibility: It ensures that the donor and recipient are compatible, reducing the risk of graft-versus-host disease (GVHD). Immunotherapy: It helps in the design of personalized immunotherapies such as CAR-T cell therapy and checkpoint inhibitors. Predicting Treatment Response: Certain HLA types are associated with better responses to specific cancer treatments, making it possible to personalize treatment plans. Vaccine Development: HLA typing is crucial for developing cancer vaccines that target specific tumor antigens.