What Are the Benefits of Using Prodrugs in Cancer Therapy?
Prodrugs offer several advantages in cancer therapy:
Targeted Delivery: Prodrugs can be designed to release the active drug specifically in the tumor microenvironment, improving the therapeutic index. Reduced Side Effects: By limiting the activation of the drug to the tumor site, prodrugs can significantly decrease adverse effects on healthy tissues. Improved Solubility: Prodrugs can be chemically modified to enhance their solubility, making them easier to administer, particularly for oral and intravenous formulations. Enhanced Stability: Prodrugs can be formulated to be more stable during storage and transport, ensuring that they retain their efficacy until they reach the target site.
