What are the biological reasons behind gender differences in cancer incidence?
The biological reasons behind gender differences in cancer incidence include hormonal variations, genetic factors, and anatomical differences. For instance, estrogen and progesterone play a significant role in the development of breast cancer in women, while testosterone influences the risk of prostate cancer in men. Genetic mutations, such as those in the BRCA1 and BRCA2 genes, also exhibit different impacts based on gender, increasing the risk of breast and ovarian cancers in women and prostate cancer in men.