Despite its advantages, the multimodal approach comes with its set of challenges:
Complexity: Coordinating multiple treatments requires meticulous planning and collaboration among different specialists. Side Effects: Each treatment modality has its own set of side effects, which can be compounded when used together. Cost: The financial burden can be significant, as multiple treatments often involve higher costs. Access to Care: Not all patients have access to the multidisciplinary teams and advanced treatments required for a multimodal approach.