What are the Challenges in Achieving High Delivery Efficiency?
Despite advancements, several challenges remain in achieving optimal delivery efficiency:
Tumor heterogeneity: Variability within and between tumors can affect how well therapeutic agents are delivered and retained. Drug resistance: Cancer cells may develop resistance to therapies, reducing the effectiveness of drug delivery. Biological barriers: Physiological barriers like the blood-brain barrier can hinder the delivery of therapeutic agents to certain tumor sites. Off-target effects: Unintended interactions with non-cancerous cells can lead to side effects and reduce the overall efficiency of the treatment.
