What are the Challenges in Achieving Lower Detection Limits?
Despite advancements, several challenges remain:
1. Biological Variability: Cancer biomarkers can vary greatly between individuals, affecting detection accuracy. 2. Sample Quality: The integrity of biological samples is crucial; degraded samples can lead to inaccurate results. 3. Cost and Accessibility: High costs and limited accessibility of advanced diagnostic technologies can hinder widespread use. 4. False Positives/Negatives: Lowering detection limits can sometimes increase the risk of false-positive or false-negative results, complicating diagnosis.
