While the benefits of data integration are immense, there are several challenges: - Data Heterogeneity: Different datasets often come in various formats and standards, making it difficult to combine them. - Data Quality: Ensuring the accuracy, completeness, and reliability of data is crucial but challenging. - Privacy and Security: Protecting patient information while sharing data for research purposes is a significant concern. - Computational Complexity: Integrating large datasets requires advanced computational resources and algorithms.