What are the Challenges in Determining Optimal Dosage?
Determining the optimal dosage is fraught with challenges:
- Variability in Patient Response: Patients can respond differently to the same dosage due to individual differences. - Side Effects: Balancing efficacy with manageable side effects can be difficult. - Drug Interactions: Patients often take multiple medications, which can interact and affect the optimal dosage. - Evolving Tumors: Tumors can evolve and develop resistance, necessitating dosage adjustments over time.