What are the challenges in developing therapeutic candidates?
The development of new cancer therapies faces several challenges:
1. Tumor Heterogeneity: Cancer cells within the same tumor can be genetically diverse, making it difficult to target all cells effectively with a single treatment. 2. Drug Resistance: Cancer cells can develop resistance to therapies over time, rendering treatments less effective. 3. Toxicity: Many potential treatments can cause significant side effects, making it difficult to balance efficacy with patient safety. 4. Delivery Mechanisms: Effectively delivering therapeutic agents to the tumor site can be challenging, especially for solid tumors.
