What are the Challenges in Drug Sensitivity Testing?
There are several challenges in drug sensitivity testing. Tumor heterogeneity means that different cells within the same tumor may respond differently to treatment. Additionally, the tumor microenvironment, including factors like blood supply and immune cells, can influence drug effectiveness. Technical limitations in replicating the complex in vivo environment in vitro also pose significant challenges. Lastly, drug resistance can develop over time, necessitating continuous monitoring and adjustment of treatment plans.
