What are the Challenges in Gene Expression Analysis?
There are several challenges in gene expression analysis in cancer: - Heterogeneity: Tumors are often heterogeneous, with different cells within the same tumor showing different gene expression profiles. - Data Interpretation: Large-scale data from techniques like RNA-seq require sophisticated bioinformatics tools to interpret. - Sample Quality: The quality of the RNA sample can greatly affect the results, and degraded RNA can lead to misleading conclusions.
