What are the Challenges in Meta-Analysis for Cancer Studies?
Meta-analysis in cancer research faces several challenges:
- Heterogeneity: Different studies often use varying methodologies, populations, and endpoints. - Publication bias: Studies with positive results are more likely to be published, skewing the data. - Quality of studies: Low-quality studies can affect the reliability of the meta-analysis. - Data availability: Access to raw data from all relevant studies is not always possible.