What are the Challenges in Methylation-Based Therapies?
Despite the potential, there are several challenges in developing effective methylation-based therapies. One major challenge is the selectivity of these drugs, as they can affect both cancerous and normal cells. Additionally, the complexity of methylation patterns across different cancer types and stages makes it difficult to design universal therapeutic strategies. More research is needed to understand the context-specific roles of methylation in cancer and to develop more targeted approaches.
