What are the Challenges in Studying Protein Expression in Cancer?
Studying protein expression in cancer presents several challenges: - Heterogeneity: Tumors are often heterogeneous, meaning that different cells within the same tumor can have different protein expression profiles. - Dynamic Changes: Protein expression can change rapidly in response to environmental factors or treatment, making it difficult to capture a static picture. - Technical Limitations: While technologies are advancing, there are still limitations in sensitivity, specificity, and throughput, which can hinder comprehensive analysis.