What are the Challenges in Targeted Gene Delivery?
Despite its potential, targeted gene delivery faces several challenges. One major issue is achieving specificityâensuring that the therapeutic genes reach only the cancer cells while avoiding healthy tissue. Another challenge is overcoming the body's immune response, which can recognize and eliminate the vectors before they reach their target. Additionally, ensuring the stability of the genetic material during delivery and achieving efficient expression of the therapeutic gene once inside the cell are critical hurdles.
