What Are the Challenges in Targeting Cancer Cells?
One of the main challenges in targeting cancer cells is their genetic and phenotypic heterogeneity. This diversity makes it difficult to develop therapies that are effective against all cancer cells within a tumor. Additionally, cancer cells can develop drug resistance through various mechanisms, including drug efflux, DNA repair, and alterations in drug targets. Overcoming these challenges requires a multifaceted approach, including the use of combination therapies and personalized medicine.