What are the Challenges of Gene Expression Profiling in Cancer?
Despite its potential, gene expression profiling faces several challenges:
Heterogeneity: Tumors are often heterogeneous, meaning they contain a mixture of different cell types, which can complicate the interpretation of profiling data. Data Complexity: The vast amount of data generated requires sophisticated bioinformatics tools and expertise to analyze and interpret. Validation: Findings from gene expression studies need to be validated in larger, independent cohorts to ensure their reliability and clinical relevance.
