What are the Challenges of Using Skin Culture in Cancer Research?
While skin culture offers numerous advantages, it also presents several challenges. One significant challenge is maintaining the complex microenvironment of the skin, which includes various cell types and extracellular matrix components. Another challenge is the potential for genetic and phenotypic changes in cultured cells over time, which may differ from their behavior in the human body. Additionally, translating findings from skin culture to clinical applications requires rigorous validation and testing.