The KPS is utilized in various clinical settings: - Prognostication: Lower KPS scores are often associated with a poorer prognosis. This can help healthcare providers discuss end-of-life care and advance directives with patients and families. - Treatment Planning: The KPS helps in determining the eligibility for certain treatments, such as chemotherapy or radiation therapy. - Clinical Trials: Many clinical trials use KPS scores as inclusion or exclusion criteria to ensure that participants can tolerate the interventions being studied. - Quality of Life Assessments: The KPS can be a component of broader assessments aimed at evaluating the quality of life of cancer patients.